Possibilities of multi-parameter ultrasonography in diagnostic and evaluation of Vitex agnus-castus treatment of patients with mastodynia and mastopathy

Objectives: 1) to determine the elasticity of normal breast tissue (parenchyma and premammary adipose tissue) in healthy women using ultrasound two-dimensional shear wave elastography (2D-SWE); 2) reveal a possible correlation between increased stiffness parenchyma hyperprolactinemia patients with mastodynia mastopathy; 3) evaluate ability Vitex agnus-castus drug reduce glandular tissue; 4) objectify affect thickness parenchyma, condition milk ducts cystic changes.Materials methods. Breast was investigated 2D (2D-SWE) 32 aged 18–52 cyclic mastalgia/mastopathy before after treatment drug. A made laboratory parameters (prolactin level), general according results ultrasonography gray scale mode. The control group consisted 78 without complaints, signs diffuse focal pathology mammary glands.Results. 2D-SWE showed values pathology. symptomatic it detect thereby screening for its changes. At same time, dynamic changes softbreast as result thickness, dilatation ducts, presence simple foci (BI-RADS 2)) were diagnosed, analyzed compared grayscale mode (2D). majority (90,6%) noted decrease level prolactin treatment. Statistical evidence positive effect mastodynia/mastopathy has been proven.Conclusions. Assessment basic makes screen elevated values. This fact assign these risk developing cancer. Evaluation mechanical properties soft tissues effectiveness